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Emergency Abdominal Surgery in the Elderly: Can We Predict Mortality?
BACKGROUND: The United Kingdom population is ageing. Half of patients requiring an emergency laparotomy are aged over 70, 20 % die within 30 days, and less than half receive good care. Frailty and delay in management are associated with poor surgical outcomes. P-POSSUM risk scoring is widely accepte...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5258798/ https://www.ncbi.nlm.nih.gov/pubmed/27783141 http://dx.doi.org/10.1007/s00268-016-3751-3 |
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author | Sharrock, Anna E. McLachlan, Jenny Chambers, Robert Bailey, Ian S. Kirkby-Bott, James |
author_facet | Sharrock, Anna E. McLachlan, Jenny Chambers, Robert Bailey, Ian S. Kirkby-Bott, James |
author_sort | Sharrock, Anna E. |
collection | PubMed |
description | BACKGROUND: The United Kingdom population is ageing. Half of patients requiring an emergency laparotomy are aged over 70, 20 % die within 30 days, and less than half receive good care. Frailty and delay in management are associated with poor surgical outcomes. P-POSSUM risk scoring is widely accepted, but its validity in patients aged over 70 undergoing emergency laparotomy is unclear. Aims: To assess if P-POSSUM risk stratification reliably predicts inpatient mortality in this group and establish whether those who died within 30 days received delayed care. METHODS: Observational study of consecutive patients aged 70 and over fulfilling the National Emergency Laparotomy Audit criteria from a tertiary hospital. The predictive value of pre-operative P-POSSUM, ASA, lactate and other routine variables was assessed. Surgical review, decision to operate, consultant surgical review, antibiotic prescription, laparotomy and discharge or death time points were assessed by 30-day survival. RESULTS: One hundred and ninety-three patients were included. This represented 46.28 % of those undergoing an emergency laparotomy in our centre. Pre-operative P-POSSUM scoring, ASA grade and lactate were moderate predictors of mortality (AUC 0.784 and 0.771, respectively, lactate AUC 0.705, all p ≤ 0.001). No correlation existed between pre-operative P-POSSUM and days to death (p = 0.209), nor were there delays in key management timings in those who died in 30 days. CONCLUSIONS: P-POSSUM scoring may predict inpatient mortality with moderate discrimination. Addition of frailty scoring in this high-risk group might better identify those with a high risk of mortality after emergency laparotomy and would be a fertile area for further research. |
format | Online Article Text |
id | pubmed-5258798 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-52587982017-02-06 Emergency Abdominal Surgery in the Elderly: Can We Predict Mortality? Sharrock, Anna E. McLachlan, Jenny Chambers, Robert Bailey, Ian S. Kirkby-Bott, James World J Surg Original Scientific Report BACKGROUND: The United Kingdom population is ageing. Half of patients requiring an emergency laparotomy are aged over 70, 20 % die within 30 days, and less than half receive good care. Frailty and delay in management are associated with poor surgical outcomes. P-POSSUM risk scoring is widely accepted, but its validity in patients aged over 70 undergoing emergency laparotomy is unclear. Aims: To assess if P-POSSUM risk stratification reliably predicts inpatient mortality in this group and establish whether those who died within 30 days received delayed care. METHODS: Observational study of consecutive patients aged 70 and over fulfilling the National Emergency Laparotomy Audit criteria from a tertiary hospital. The predictive value of pre-operative P-POSSUM, ASA, lactate and other routine variables was assessed. Surgical review, decision to operate, consultant surgical review, antibiotic prescription, laparotomy and discharge or death time points were assessed by 30-day survival. RESULTS: One hundred and ninety-three patients were included. This represented 46.28 % of those undergoing an emergency laparotomy in our centre. Pre-operative P-POSSUM scoring, ASA grade and lactate were moderate predictors of mortality (AUC 0.784 and 0.771, respectively, lactate AUC 0.705, all p ≤ 0.001). No correlation existed between pre-operative P-POSSUM and days to death (p = 0.209), nor were there delays in key management timings in those who died in 30 days. CONCLUSIONS: P-POSSUM scoring may predict inpatient mortality with moderate discrimination. Addition of frailty scoring in this high-risk group might better identify those with a high risk of mortality after emergency laparotomy and would be a fertile area for further research. Springer International Publishing 2016-10-25 2017 /pmc/articles/PMC5258798/ /pubmed/27783141 http://dx.doi.org/10.1007/s00268-016-3751-3 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Original Scientific Report Sharrock, Anna E. McLachlan, Jenny Chambers, Robert Bailey, Ian S. Kirkby-Bott, James Emergency Abdominal Surgery in the Elderly: Can We Predict Mortality? |
title | Emergency Abdominal Surgery in the Elderly: Can We Predict Mortality? |
title_full | Emergency Abdominal Surgery in the Elderly: Can We Predict Mortality? |
title_fullStr | Emergency Abdominal Surgery in the Elderly: Can We Predict Mortality? |
title_full_unstemmed | Emergency Abdominal Surgery in the Elderly: Can We Predict Mortality? |
title_short | Emergency Abdominal Surgery in the Elderly: Can We Predict Mortality? |
title_sort | emergency abdominal surgery in the elderly: can we predict mortality? |
topic | Original Scientific Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5258798/ https://www.ncbi.nlm.nih.gov/pubmed/27783141 http://dx.doi.org/10.1007/s00268-016-3751-3 |
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