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IL-22-producing CD4+T cells in the treatment response of rheumatoid arthritis to combination therapy with methotrexate and leflunomide
T cells are key players in immune-mediated rheumatoid arthritis (RA). We previously reported that interleukin (IL)-22(+)CD4(+)T helper (IL-22(+) Th) cells and IL-22 critically control the pathogenesis of RA. Here we monitored circulating levels of different IL-22(+) Th cell subsets and measured plas...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259708/ https://www.ncbi.nlm.nih.gov/pubmed/28117352 http://dx.doi.org/10.1038/srep41143 |