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NLRP3 inflammasome: Pathogenic role and potential therapeutic target for IgA nephropathy

We have previously showed that IL-1β is involved in the pathogenesis of both spontaneously occurring and passively induced IgA nephropathy (IgAN) models. However, the exact causal-relationship between NLRP3 inflammasome and the pathogenesis of IgAN remains unknown. In the present study, we showed th...

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Detalles Bibliográficos
Autores principales: Tsai, Yu-Ling, Hua, Kuo-Feng, Chen, Ann, Wei, Chyou-Wei, Chen, Wen-Shiang, Wu, Cheng-Yeu, Chu, Ching-Liang, Yu, Yung-Luen, Lo, Chia-Wen, Ka, Shuk-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259731/
https://www.ncbi.nlm.nih.gov/pubmed/28117341
http://dx.doi.org/10.1038/srep41123