Time-of-Day Dictates Transcriptional Inflammatory Responses to Cytotoxic Chemotherapy

Many cytotoxic chemotherapeutics elicit a proinflammatory response which is often associated with chemotherapy-induced behavioral alterations. The immune system is under circadian influence; time-of-day may alter inflammatory responses to chemotherapeutics. We tested this hypothesis by administering...

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Detalles Bibliográficos
Autores principales: Borniger, Jeremy C., Walker II, William H., Gaudier-Diaz, Monica M., Stegman, Curtis J., Zhang, Ning, Hollyfield, Jennifer L., Nelson, Randy J., DeVries, A. Courtney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259749/
https://www.ncbi.nlm.nih.gov/pubmed/28117419
http://dx.doi.org/10.1038/srep41220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259749/
https://www.ncbi.nlm.nih.gov/pubmed/28117419
http://dx.doi.org/10.1038/srep41220

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