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Selective inhibition of Ebola entry with selective estrogen receptor modulators by disrupting the endolysosomal calcium

The Ebola crisis occurred in West-Africa highlights the urgency for its clinical treatments. Currently, no Food and Drug Administration (FDA)-approved therapeutics are available. Several FDA-approved drugs, including selective estrogen receptor modulators (SERMs), possess selective anti-Ebola activi...

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Detalles Bibliográficos
Autores principales: Fan, Hanlu, Du, Xiaohong, Zhang, Jingyuan, Zheng, Han, Lu, Xiaohui, Wu, Qihui, Li, Haifeng, Wang, Han, Shi, Yi, Gao, George, Zhou, Zhuan, Tan, Dun-Xian, Li, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259750/
https://www.ncbi.nlm.nih.gov/pubmed/28117364
http://dx.doi.org/10.1038/srep41226