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The Global Relationship between Chromatin Physical Topology, Fractal Structure, and Gene Expression
Most of what we know about gene transcription comes from the view of cells as molecular machines: focusing on the role of molecular modifications to the proteins carrying out transcriptional reactions at a loci-by-loci basis. This view ignores a critical reality: biological reactions do not happen i...
Autores principales: | Almassalha, L. M., Tiwari, A., Ruhoff, P. T., Stypula-Cyrus, Y., Cherkezyan, L., Matsuda, H., Dela Cruz, M. A., Chandler, J. E., White, C., Maneval, C., Subramanian, H., Szleifer, I., Roy, H. K., Backman, V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259786/ https://www.ncbi.nlm.nih.gov/pubmed/28117353 http://dx.doi.org/10.1038/srep41061 |
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