A compound-based proteomic approach discloses 15-ketoatractyligenin methyl ester as a new PPARγ partial agonist with anti-proliferative ability

Proteomics based approaches are emerging as useful tools to identify the targets of bioactive compounds and elucidate their molecular mechanisms of action. Here, we applied a chemical proteomic strategy to identify the peroxisome proliferator-activated receptor γ (PPARγ) as a molecular target of the...

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Detalles Bibliográficos
Autores principales: Vasaturo, Michele, Fiengo, Lorenzo, De Tommasi, Nunziatina, Sabatino, Lina, Ziccardi, Pamela, Colantuoni, Vittorio, Bruno, Maurizio, Cerchia, Carmen, Novellino, Ettore, Lupo, Angelo, Lavecchia, Antonio, Piaz, Fabrizio Dal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259791/
https://www.ncbi.nlm.nih.gov/pubmed/28117438
http://dx.doi.org/10.1038/srep41273

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