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Modelling mutational landscapes of human cancers in vitro

Experimental models that recapitulate mutational landscapes of human cancers are needed to decipher the rapidly expanding data on human somatic mutations. We demonstrate that mutation patterns in immortalised cell lines derived from primary murine embryonic fibroblasts (MEFs) exposed in vitro to car...

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Detalles Bibliográficos
Autores principales:	Olivier, Magali, Weninger, Annette, Ardin, Maude, Huskova, Hana, Castells, Xavier, Vallée, Maxime P., McKay, James, Nedelko, Tatiana, Muehlbauer, Karl-Rudolf, Marusawa, Hiroyuki, Alexander, John, Hazelwood, Lee, Byrnes, Graham, Hollstein, Monica, Zavadil, Jiri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259794/ https://www.ncbi.nlm.nih.gov/pubmed/24670820 http://dx.doi.org/10.1038/srep04482

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