Impairment of blood-brain barrier is an early event in R6/2 mouse model of Huntington Disease

Blood-brain barrier (BBB) breakdown, due to the concomitant disruption of the tight junctions (TJs), normally required for the maintenance of BBB function, and to the altered transport of molecules between blood and brain and vice-versa, has been suggested to significantly contribute to the developm...

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Detalles Bibliográficos
Autores principales: Di Pardo, Alba, Amico, Enrico, Scalabrì, Francesco, Pepe, Giuseppe, Castaldo, Salvatore, Elifani, Francesca, Capocci, Luca, De Sanctis, Claudia, Comerci, Laura, Pompeo, Francesco, D’Esposito, Maurizio, Filosa, Stefania, Crispi, Stefania, Maglione, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259798/
https://www.ncbi.nlm.nih.gov/pubmed/28117381
http://dx.doi.org/10.1038/srep41316

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