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Inferring new indications for approved drugs via random walk on drug-disease heterogenous networks
BACKGROUND: Since traditional drug research and development is often time-consuming and high-risk, there is an increasing interest in establishing new medical indications for approved drugs, referred to as drug repositioning, which provides a relatively low-cost and high-efficiency approach for drug...
Autores principales: | Liu, Hui, Song, Yinglong, Guan, Jihong, Luo, Libo, Zhuang, Ziheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259862/ https://www.ncbi.nlm.nih.gov/pubmed/28155639 http://dx.doi.org/10.1186/s12859-016-1336-7 |
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