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Drug-target interaction prediction via class imbalance-aware ensemble learning

BACKGROUND: Multiple computational methods for predicting drug-target interactions have been developed to facilitate the drug discovery process. These methods use available data on known drug-target interactions to train classifiers with the purpose of predicting new undiscovered interactions. Howev...

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Detalles Bibliográficos
Autores principales: Ezzat, Ali, Wu, Min, Li, Xiao-Li, Kwoh, Chee-Keong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259867/
https://www.ncbi.nlm.nih.gov/pubmed/28155697
http://dx.doi.org/10.1186/s12859-016-1377-y