Optimizing mesoderm progenitor selection and three-dimensional microniche culture allows highly efficient endothelial differentiation and ischemic tissue repair from human pluripotent stem cells

BACKGROUND: Generation of large quantities of endothelial cells is highly desirable for vascular research, for the treatment of ischemia diseases, and for tissue regeneration. To achieve this goal, we developed a simple, chemically defined culture system to efficiently and rapidly differentiate endo...

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Detalles Bibliográficos
Autores principales: Zhang, Fengzhi, Wang, Lin, Li, Yaqian, Liu, Wei, Duan, Fuyu, Huang, Rujin, Chen, Xi, Chang, Sophia Chia-Ning, Du, Yanan, Na, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259899/
https://www.ncbi.nlm.nih.gov/pubmed/28114972
http://dx.doi.org/10.1186/s13287-016-0455-4

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