Sig2GRN: a software tool linking signaling pathway with gene regulatory network for dynamic simulation

BACKGROUND: Linking computational models of signaling pathways to predicted cellular responses such as gene expression regulation is a major challenge in computational systems biology. In this work, we present Sig2GRN, a Cytoscape plugin that is able to simulate time-course gene expression data give...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Fan, Liu, Runsheng, Zheng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259907/
https://www.ncbi.nlm.nih.gov/pubmed/28155685
http://dx.doi.org/10.1186/s12918-016-0365-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259907/
https://www.ncbi.nlm.nih.gov/pubmed/28155685
http://dx.doi.org/10.1186/s12918-016-0365-1

Ejemplares similares