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Sig2GRN: a software tool linking signaling pathway with gene regulatory network for dynamic simulation
BACKGROUND: Linking computational models of signaling pathways to predicted cellular responses such as gene expression regulation is a major challenge in computational systems biology. In this work, we present Sig2GRN, a Cytoscape plugin that is able to simulate time-course gene expression data give...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259907/ https://www.ncbi.nlm.nih.gov/pubmed/28155685 http://dx.doi.org/10.1186/s12918-016-0365-1 |