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Influence of endoleak positions on the pressure shielding ability of stent-graft after endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA)

BACKGROUND: Abdominal aortic aneurysm (AAA) is a kind of dangerous aortic vascular disease, which is characterized by abdominal aorta partial enlargement. At present, endovascular aneurysm repair (EVAR) is one of the main treatments of abdominal aortic aneurysm. However for some patients after EVAR...

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Autores principales: Li, Jie, Tian, Xiaopeng, Wang, Zhenze, Xiong, Jiang, Fan, Yubo, Deng, Xiaoyan, Sun, Anqiang, Liu, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259942/
https://www.ncbi.nlm.nih.gov/pubmed/28155691
http://dx.doi.org/10.1186/s12938-016-0249-z
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author Li, Jie
Tian, Xiaopeng
Wang, Zhenze
Xiong, Jiang
Fan, Yubo
Deng, Xiaoyan
Sun, Anqiang
Liu, Xiao
author_facet Li, Jie
Tian, Xiaopeng
Wang, Zhenze
Xiong, Jiang
Fan, Yubo
Deng, Xiaoyan
Sun, Anqiang
Liu, Xiao
author_sort Li, Jie
collection PubMed
description BACKGROUND: Abdominal aortic aneurysm (AAA) is a kind of dangerous aortic vascular disease, which is characterized by abdominal aorta partial enlargement. At present, endovascular aneurysm repair (EVAR) is one of the main treatments of abdominal aortic aneurysm. However for some patients after EVAR the aneurysm re-expanded and even ruptured, leading to poor postoperative effect. The stent-graft endoleak after EVAR was realized to influence the AAA in-sac pressure and contribute to the aneurysm re-enlargement. METHODS: In order to analyze the influence of endoleaks positions on the pressure shielding ability of stent-graft after EVAR, type I and type III endoleak models were reconstructed based on computed tomography (CT) scan images, and the hemodynamic environment in AAA was numerically simulated. RESULTS: When the endoleak was at the proximal position the pressure shielding ability will be obviously weakened. While, the pressure shielding ability was higher in the systole phase than that in diastole phase when the endoleak located at the middle or distal positions. Unfortunately, when the endoleak located at the proximal position, the pressure shielding ability would be relatively weak in the whole cardiac cycle. CONCLUSIONS: The results revealed that the influence of endoleaks on pressure shielding ability of stent-graft was both location and time specific.
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spelling pubmed-52599422017-01-26 Influence of endoleak positions on the pressure shielding ability of stent-graft after endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA) Li, Jie Tian, Xiaopeng Wang, Zhenze Xiong, Jiang Fan, Yubo Deng, Xiaoyan Sun, Anqiang Liu, Xiao Biomed Eng Online Research BACKGROUND: Abdominal aortic aneurysm (AAA) is a kind of dangerous aortic vascular disease, which is characterized by abdominal aorta partial enlargement. At present, endovascular aneurysm repair (EVAR) is one of the main treatments of abdominal aortic aneurysm. However for some patients after EVAR the aneurysm re-expanded and even ruptured, leading to poor postoperative effect. The stent-graft endoleak after EVAR was realized to influence the AAA in-sac pressure and contribute to the aneurysm re-enlargement. METHODS: In order to analyze the influence of endoleaks positions on the pressure shielding ability of stent-graft after EVAR, type I and type III endoleak models were reconstructed based on computed tomography (CT) scan images, and the hemodynamic environment in AAA was numerically simulated. RESULTS: When the endoleak was at the proximal position the pressure shielding ability will be obviously weakened. While, the pressure shielding ability was higher in the systole phase than that in diastole phase when the endoleak located at the middle or distal positions. Unfortunately, when the endoleak located at the proximal position, the pressure shielding ability would be relatively weak in the whole cardiac cycle. CONCLUSIONS: The results revealed that the influence of endoleaks on pressure shielding ability of stent-graft was both location and time specific. BioMed Central 2016-12-28 /pmc/articles/PMC5259942/ /pubmed/28155691 http://dx.doi.org/10.1186/s12938-016-0249-z Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Li, Jie
Tian, Xiaopeng
Wang, Zhenze
Xiong, Jiang
Fan, Yubo
Deng, Xiaoyan
Sun, Anqiang
Liu, Xiao
Influence of endoleak positions on the pressure shielding ability of stent-graft after endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA)
title Influence of endoleak positions on the pressure shielding ability of stent-graft after endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA)
title_full Influence of endoleak positions on the pressure shielding ability of stent-graft after endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA)
title_fullStr Influence of endoleak positions on the pressure shielding ability of stent-graft after endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA)
title_full_unstemmed Influence of endoleak positions on the pressure shielding ability of stent-graft after endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA)
title_short Influence of endoleak positions on the pressure shielding ability of stent-graft after endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA)
title_sort influence of endoleak positions on the pressure shielding ability of stent-graft after endovascular aneurysm repair (evar) of abdominal aortic aneurysm (aaa)
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259942/
https://www.ncbi.nlm.nih.gov/pubmed/28155691
http://dx.doi.org/10.1186/s12938-016-0249-z
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