Prognostic and therapeutic value of disruptor of telomeric silencing-1-like (DOT1L) expression in patients with ovarian cancer

BACKGROUND: Epigenetics has been known to play a critical role in regulating the malignant phenotype. This study was designed to examine the expression of DOT1L (histone 3 lysine 79 methyltransferase) and H3K79 methylation in normal ovarian tissues and ovarian tumors and to explore the function of D...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoxue, Liu, Dan, Li, Mengchen, Cao, Canhui, Wan, Dongyi, Xi, Bixin, Li, Wenqian, Tan, Jiahong, Wang, Ji, Wu, Zhongcai, Ma, Ding, Gao, Qinglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259947/
https://www.ncbi.nlm.nih.gov/pubmed/28114995
http://dx.doi.org/10.1186/s13045-017-0400-8

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