HIV signaling through CD4 and CCR5 activates Rho family GTPases that are required for optimal infection of primary CD4+ T cells

BACKGROUND: HIV-1 hijacks host cell machinery to ensure successful replication, including cytoskeletal components for intracellular trafficking, nucleoproteins for pre-integration complex import, and the ESCRT pathway for assembly and budding. It is widely appreciated that cellular post-translationa...

Descripción completa

Detalles Bibliográficos
Autores principales: Lucera, Mark B., Fleissner, Zach, Tabler, Caroline O., Schlatzer, Daniela M., Troyer, Zach, Tilton, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259950/
https://www.ncbi.nlm.nih.gov/pubmed/28114951
http://dx.doi.org/10.1186/s12977-017-0328-7

Ejemplares similares

Ejemplares similares