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An ensemble micro neural network approach for elucidating interactions between zinc finger proteins and their target DNA
BACKGROUND: The ability to engineer zinc finger proteins binding to a DNA sequence of choice is essential for targeted genome editing to be possible. Experimental techniques and molecular docking have been successful in predicting protein-DNA interactions, however, they are highly time and resource...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260015/ https://www.ncbi.nlm.nih.gov/pubmed/28155662 http://dx.doi.org/10.1186/s12864-016-3323-9 |