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Genome-wide functional analysis using the barcode sequence alignment and statistical analysis (Barcas) tool

BACKGROUND: Pooled library screen analysis using shRNAs or CRISPR-Cas9 hold great promise to genome-wide functional studies. While pooled library screens are effective tools, erroneous barcodes can potentially be generated during the production of many barcodes. However, no current tools can disting...

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Detalles Bibliográficos
Autores principales: Mun, Jihyeob, Kim, Dong-Uk, Hoe, Kwang-Lae, Kim, Seon-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260075/
https://www.ncbi.nlm.nih.gov/pubmed/28155635
http://dx.doi.org/10.1186/s12859-016-1326-9