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Genome-wide functional analysis using the barcode sequence alignment and statistical analysis (Barcas) tool
BACKGROUND: Pooled library screen analysis using shRNAs or CRISPR-Cas9 hold great promise to genome-wide functional studies. While pooled library screens are effective tools, erroneous barcodes can potentially be generated during the production of many barcodes. However, no current tools can disting...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260075/ https://www.ncbi.nlm.nih.gov/pubmed/28155635 http://dx.doi.org/10.1186/s12859-016-1326-9 |