Statistical ensemble of gene regulatory networks of macrophage differentiation

BACKGROUND: Macrophages cover a major role in the immune system, being the most plastic cell yielding several key immune functions. METHODS: Here we derived a minimalistic gene regulatory network model for the differentiation of macrophages into the two phenotypes M1 (pro-) and M2 (anti-inflammatory...

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Detalles Bibliográficos
Autores principales: Castiglione, Filippo, Tieri, Paolo, Palma, Alessandro, Jarrah, Abdul Salam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260144/
https://www.ncbi.nlm.nih.gov/pubmed/28155642
http://dx.doi.org/10.1186/s12859-016-1363-4

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