Long-term exposure to bisphenol A or benzo(a)pyrene alters the fate of human mammary epithelial stem cells in response to BMP2 and BMP4, by pre-activating BMP signaling

Bone morphogenetic protein 2 (BMP2) and BMP4 are key regulators of the fate and differentiation of human mammary epithelial stem cells (SCs), as well as of their niches, and are involved in breast cancer development. We established that MCF10A immature mammary epithelial cells reliably reproduce the...

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Detalles Bibliográficos
Autores principales: Clément, Flora, Xu, Xinyi, Donini, Caterina F, Clément, Alice, Omarjee, Soleilmane, Delay, Emmanuel, Treilleux, Isabelle, Fervers, Béatrice, Le Romancer, Muriel, Cohen, Pascale A, Maguer-Satta, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260492/
https://www.ncbi.nlm.nih.gov/pubmed/27740625
http://dx.doi.org/10.1038/cdd.2016.107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260492/
https://www.ncbi.nlm.nih.gov/pubmed/27740625
http://dx.doi.org/10.1038/cdd.2016.107

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