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Long-term exposure to bisphenol A or benzo(a)pyrene alters the fate of human mammary epithelial stem cells in response to BMP2 and BMP4, by pre-activating BMP signaling
Bone morphogenetic protein 2 (BMP2) and BMP4 are key regulators of the fate and differentiation of human mammary epithelial stem cells (SCs), as well as of their niches, and are involved in breast cancer development. We established that MCF10A immature mammary epithelial cells reliably reproduce the...
Autores principales: | Clément, Flora, Xu, Xinyi, Donini, Caterina F, Clément, Alice, Omarjee, Soleilmane, Delay, Emmanuel, Treilleux, Isabelle, Fervers, Béatrice, Le Romancer, Muriel, Cohen, Pascale A, Maguer-Satta, Véronique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260492/ https://www.ncbi.nlm.nih.gov/pubmed/27740625 http://dx.doi.org/10.1038/cdd.2016.107 |
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