ER stress inhibitor attenuates hearing loss and hair cell death in Cdh23(erl/erl) mutant mice

Hearing loss is one of the most common sensory impairments in humans. Mouse mutant models helped us to better understand the mechanisms of hearing loss. Recently, we have discovered that the erlong (erl) mutation of the cadherin23 (Cdh23) gene leads to hearing loss due to hair cell apoptosis. In thi...

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Detalles Bibliográficos
Autores principales: Hu, Juan, Li, Bo, Apisa, Luke, Yu, Heping, Entenman, Shami, Xu, Min, Stepanyan, Ruben, Guan, Bo-Jhih, Müller, Ulrich, Hatzoglou, Maria, Zheng, Qing Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260868/
https://www.ncbi.nlm.nih.gov/pubmed/27882946
http://dx.doi.org/10.1038/cddis.2016.386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260868/
https://www.ncbi.nlm.nih.gov/pubmed/27882946
http://dx.doi.org/10.1038/cddis.2016.386

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