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ER stress inhibitor attenuates hearing loss and hair cell death in Cdh23(erl/erl) mutant mice
Hearing loss is one of the most common sensory impairments in humans. Mouse mutant models helped us to better understand the mechanisms of hearing loss. Recently, we have discovered that the erlong (erl) mutation of the cadherin23 (Cdh23) gene leads to hearing loss due to hair cell apoptosis. In thi...
Autores principales: | Hu, Juan, Li, Bo, Apisa, Luke, Yu, Heping, Entenman, Shami, Xu, Min, Stepanyan, Ruben, Guan, Bo-Jhih, Müller, Ulrich, Hatzoglou, Maria, Zheng, Qing Yin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260868/ https://www.ncbi.nlm.nih.gov/pubmed/27882946 http://dx.doi.org/10.1038/cddis.2016.386 |
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