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Activation and cleavage of SASH1 by caspase-3 mediates an apoptotic response

Apoptosis is a highly regulated cellular process that functions to remove undesired cells from multicellular organisms. This pathway is often disrupted in cancer, providing tumours with a mechanism to avoid cell death and promote growth and survival. The putative tumour suppressor, SASH1 (SAM and SH...

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Detalles Bibliográficos
Autores principales:	Burgess, Joshua T, Bolderson, Emma, Adams, Mark N, Baird, Anne-Marie, Zhang, Shu-Dong, Gately, Kathy A, Umezawa, Kazuo, O'Byrne, Kenneth J, Richard, Derek J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260870/ https://www.ncbi.nlm.nih.gov/pubmed/27831555 http://dx.doi.org/10.1038/cddis.2016.364

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