Phospholipase D1-regulated autophagy supplies free fatty acids to counter nutrient stress in cancer cells

Cancer cells utilize flexible metabolic programs to maintain viability and proliferation under stress conditions including nutrient deprivation. Here we report that phospholipase D1 (PLD1) participates in the regulation of metabolic plasticity in cancer cells. PLD1 activity is required for cancer ce...

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Detalles Bibliográficos
Autores principales: Cai, Ming, He, Jingquan, Xiong, Jian, Tay, Li Wei Rachel, Wang, Ziqing, Rog, Colin, Wang, Jingshu, Xie, Yizhao, Wang, Guobin, Banno, Yoshiko, Li, Feng, Zhu, Michael, Du, Guangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260880/
https://www.ncbi.nlm.nih.gov/pubmed/27809301
http://dx.doi.org/10.1038/cddis.2016.355

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