Downregulation of microRNA-27b-3p enhances tamoxifen resistance in breast cancer by increasing NR5A2 and CREB1 expression

Estrogen-dependent breast cancer is often treated with the aromatase inhibitors or estrogen receptor (ER) antagonists. Tamoxifen as a major ER antagonist is usually used to treat those patients with ERα-positive breast cancer. However, a majority of patients with ERα positive fail to respond to tamo...

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Detalles Bibliográficos
Autores principales: Zhu, Jiang, Zou, Zhengzhi, Nie, Peipei, Kou, Xiaoni, Wu, Baoyan, Wang, Songmao, Song, Zhangjun, He, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260890/
https://www.ncbi.nlm.nih.gov/pubmed/27809310
http://dx.doi.org/10.1038/cddis.2016.361

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