Downregulation of ASPP2 improves hepatocellular carcinoma cells survival via promoting BECN1-dependent autophagy initiation

Autophagy is an important catabolic process, which sustains intracellular homeostasis and lengthens cell survival under stress. Here we identify the ankyrin-repeat-containing, SH3-domain-containing, and proline-rich region-containing protein 2 (ASPP2), a haploinsufficient tumor suppressor, as a mole...

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Detalles Bibliográficos
Autores principales: Chen, Rui, Wang, Hao, Liang, Beibei, Liu, Guoke, Tang, Min, Jia, Rongjie, Fan, Xiaoyu, Jing, Wei, Zhou, Xuyu, Wang, Huajing, Yang, Yang, Wei, Huafeng, Li, Bohua, Zhao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260975/
https://www.ncbi.nlm.nih.gov/pubmed/27929538
http://dx.doi.org/10.1038/cddis.2016.407

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