Hypericin-mediated sonodynamic therapy induces autophagy and decreases lipids in THP-1 macrophage by promoting ROS-dependent nuclear translocation of TFEB

Lipid catabolism disorder is the primary cause of atherosclerosis. Transcription factor EB (TFEB) prevents atherosclerosis by activating macrophage autophagy to promote lipid degradation. Hypericin-mediated sonodynamic therapy (HY-SDT) has been proved non-invasively inducing THP-1-derived macrophage...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xuesong, Zhang, Xin, Zheng, Longbin, Kou, Jiayuan, Zhong, Zhaoyu, Jiang, Yueqing, Wang, Wei, Dong, Zengxiang, Liu, Zhongni, Han, Xiaobo, Li, Jing, Tian, Ye, Zhao, Yajun, Yang, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260986/
https://www.ncbi.nlm.nih.gov/pubmed/28005078
http://dx.doi.org/10.1038/cddis.2016.433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260986/
https://www.ncbi.nlm.nih.gov/pubmed/28005078
http://dx.doi.org/10.1038/cddis.2016.433

Ejemplares similares