The Yersinia Type III secretion effector YopM Is an E3 ubiquitin ligase that induced necrotic cell death by targeting NLRP3

Yersinia pestis uses type III effector proteins to target eukaryotic signaling systems. The Yersinia outer protein (Yop) M effector from the Y. pestis strain is a critical virulence determinant; however, its role in Y. pestis pathogenesis is just beginning to emerge. Here we first identify YopM as t...

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Detalles Bibliográficos
Autores principales: Wei, Congwen, Wang, Ying, Du, Zongmin, Guan, Kai, Cao, Ye, Yang, Huiying, Zhou, Pengyu, Wu, Feixiang, Chen, Jiankang, Wang, Penghao, Zheng, Zirui, Zhang, Pingping, Zhang, Yanhong, Ma, Shengli, Yang, Ruifu, Zhong, Hui, He, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260993/
https://www.ncbi.nlm.nih.gov/pubmed/27929533
http://dx.doi.org/10.1038/cddis.2016.413

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