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Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis
Macrophages engulf and destroy pathogens (phagocytosis) and apoptotic cells (efferocytosis), and can subsequently initiate adaptive immune responses by presenting antigens derived from engulfed materials. Both phagocytosis and efferocytosis share a common degradative pathway in which the target is e...
Autores principales: | Yin, Charles, Kim, Yohan, Argintaru, Dean, Heit, Bryan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261003/ https://www.ncbi.nlm.nih.gov/pubmed/28005073 http://dx.doi.org/10.1038/cddis.2016.431 |
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