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Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis

Myofibroblasts play a central role in renal fibrosis although the origin of these cells remains controversial. We recently reported that bone marrow-derived macrophages can give rise to myofibroblasts through macrophage to myofibroblast transition (MMT). However, several important issues remain to b...

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Detalles Bibliográficos
Autores principales: Meng, Xiao-Ming, Wang, Shuang, Huang, Xiao-Ru, Yang, Chen, Xiao, Jun, Zhang, Yang, To, Ka-Fai, Nikolic-Paterson, David J, Lan, Hui-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261004/
https://www.ncbi.nlm.nih.gov/pubmed/27906172
http://dx.doi.org/10.1038/cddis.2016.402