PINK1-dependent phosphorylation of PINK1 and Parkin is essential for mitochondrial quality control

Mitochondrial dysfunction has been linked to the pathogenesis of a large number of inherited diseases in humans, including Parkinson's disease, the second most common neurodegenerative disorder. The Parkinson's disease genes pink1 and parkin, which encode a mitochondrially targeted protein...

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Detalles Bibliográficos
Autores principales: Zhuang, Na, Li, Lin, Chen, She, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261015/
https://www.ncbi.nlm.nih.gov/pubmed/27906179
http://dx.doi.org/10.1038/cddis.2016.396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261015/
https://www.ncbi.nlm.nih.gov/pubmed/27906179
http://dx.doi.org/10.1038/cddis.2016.396

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