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PINK1-dependent phosphorylation of PINK1 and Parkin is essential for mitochondrial quality control
Mitochondrial dysfunction has been linked to the pathogenesis of a large number of inherited diseases in humans, including Parkinson's disease, the second most common neurodegenerative disorder. The Parkinson's disease genes pink1 and parkin, which encode a mitochondrially targeted protein...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261015/ https://www.ncbi.nlm.nih.gov/pubmed/27906179 http://dx.doi.org/10.1038/cddis.2016.396 |