Osteopontin facilitates tumor metastasis by regulating epithelial–mesenchymal plasticity

Tumor metastasis leads to high mortality; therefore, understanding the mechanisms that underlie tumor metastasis is crucial. Generally seen as a secretory protein, osteopontin (OPN) is involved in multifarious pathophysiological events. Here, we present a novel pro-metastatic role of OPN during meta...

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Detalles Bibliográficos
Autores principales: Jia, Rongjie, Liang, Yingchao, Chen, Rui, Liu, Guoke, Wang, Hao, Tang, Min, Zhou, Xuyu, Wang, Huajing, Yang, Yang, Wei, Huafeng, Li, Bohua, Song, Yipeng, Zhao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261026/
https://www.ncbi.nlm.nih.gov/pubmed/28032860
http://dx.doi.org/10.1038/cddis.2016.422

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