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Effect of roll compaction on granule size distribution of microcrystalline cellulose–mannitol mixtures: computational intelligence modeling and parametric analysis

Dry granulation using roll compaction is a typical unit operation for producing solid dosage forms in the pharmaceutical industry. Dry granulation is commonly used if the powder mixture is sensitive to heat and moisture and has poor flow properties. The output of roll compaction is compacted ribbons...

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Detalles Bibliográficos
Autores principales:	Kazemi, Pezhman, Khalid, Mohammad Hassan, Pérez Gago, Ana, Kleinebudde, Peter, Jachowicz, Renata, Szlęk, Jakub, Mendyk, Aleksander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261554/ https://www.ncbi.nlm.nih.gov/pubmed/28176905 http://dx.doi.org/10.2147/DDDT.S124670

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