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γH2Ax Expression as a Potential Biomarker Differentiating between Low and High Grade Cervical Squamous Intraepithelial Lesions (SIL) and High Risk HPV Related SIL

BACKGROUND: γH2AX is a protein biomarker for double-stranded DNA breakage; its expression was studied in cervical squamous intraepithelial lesions and carcinomas. METHODS: Immunostaining for phospho-γH2AX was performed in sections from histologically confirmed cervical SIL and carcinomas, as well as...

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Detalles Bibliográficos
Autores principales: Leventakos, Konstantinos, Tsiodras, Sotirios, Kelesidis, Theodore, Kefala, Maria, Kottaridi, Christine, Spathis, Aris, Gouloumi, Alina-Roxani, Pouliakis, Abraham, Pappas, Asimakis, Sioulas, Vasileios, Chrelias, Charalambos, Karakitsos, Petros, Panayiotides, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261776/
https://www.ncbi.nlm.nih.gov/pubmed/28118377
http://dx.doi.org/10.1371/journal.pone.0170626

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