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MEDICI: Mining Essentiality Data to Identify Critical Interactions for Cancer Drug Target Discovery and Development
Protein-protein interactions (PPIs) mediate the transmission and regulation of oncogenic signals that are essential to cellular proliferation and survival, and thus represent potential targets for anti-cancer therapeutic discovery. Despite their significance, there is no method to experimentally dis...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261804/ https://www.ncbi.nlm.nih.gov/pubmed/28118365 http://dx.doi.org/10.1371/journal.pone.0170339 |