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Modelling Systemic Iron Regulation during Dietary Iron Overload and Acute Inflammation: Role of Hepcidin-Independent Mechanisms
Systemic iron levels must be maintained in physiological concentrations to prevent diseases associated with iron deficiency or iron overload. A key role in this process plays ferroportin, the only known mammalian transmembrane iron exporter, which releases iron from duodenal enterocytes, hepatocytes...
Autores principales: | Enculescu, Mihaela, Metzendorf, Christoph, Sparla, Richard, Hahnel, Maximilian, Bode, Johannes, Muckenthaler, Martina U., Legewie, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261815/ https://www.ncbi.nlm.nih.gov/pubmed/28068331 http://dx.doi.org/10.1371/journal.pcbi.1005322 |
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