Cargando…

Peripherally acting μ-opioid receptor antagonists as treatment options for constipation in noncancer pain patients on chronic opioid therapy

Opioid-induced constipation (OIC), a prevalent and distressing side effect of opioid therapy, does not reliably respond to treatment with conventional laxatives. OIC can be a treatment-limiting adverse event. Recent advances in medications with peripherally acting μ-opioid receptor antagonists, such...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pergolizzi, Joseph V, Raffa, Robert B, Pappagallo, Marco, Fleischer, Charles, Pergolizzi, Joseph, Zampogna, Gianpietro, Duval, Elizabeth, Hishmeh, Janan, LeQuang, Jo Ann, Taylor, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261842/ https://www.ncbi.nlm.nih.gov/pubmed/28176913 http://dx.doi.org/10.2147/PPA.S78042

Ejemplares similares

The Use of Peripheral μ-Opioid Receptor Antagonists (PAMORA) in the Management of Opioid-Induced Constipation: An Update on Their Efficacy and Safety
por: Pergolizzi Jr, Joseph V, et al.
Publicado: (2020)

The Basic Pharmacology of Opioids Informs the Opioid Discourse about Misuse and Abuse: A Review
por: Pergolizzi, Joseph V., et al.
Publicado: (2017)

Naltrexone extended-release injection: an option for the management of opioid abuse
por: Taylor, Robert, et al.
Publicado: (2011)

A Guide for Pain Management in Low and Middle Income Communities. Managing the Risk of Opioid Abuse in Patients with Cancer Pain
por: Pergolizzi, Joseph V., et al.
Publicado: (2016)

Stopping or Decreasing Opioid Therapy in Patients on Chronic Opioid Therapy
por: Pergolizzi, Joseph V., et al.
Publicado: (2019)

Efficacy and Safety of Peripherally Acting μ-Opioid Receptor Antagonist (PAMORAs) for the Management of Patients With Opioid-Induced Constipation: A Systematic Review
por: Rekatsina, Martina, et al.
Publicado: (2021)

Designing Opioids That Deter Abuse
por: Raffa, Robert B., et al.
Publicado: (2012)

The Role of Lofexidine in Management of Opioid Withdrawal
por: Pergolizzi, Joseph V., et al.
Publicado: (2018)

How Opioids Changed What We Thought About Addiction and the Implications for Public Health: An Editorial
por: Pergolizzi, Joseph, et al.
Publicado: (2023)

Management of moderate to severe chronic low back pain with buprenorphine buccal film using novel bioerodible mucoadhesive technology
por: Pergolizzi, Joseph V, et al.
Publicado: (2016)

Three Years Down the Road: The Aftermath of the CDC Guideline for Prescribing Opioids for Chronic Pain
por: Pergolizzi, Joseph V., et al.
Publicado: (2019)

Statins and Neuropathic Pain: A Narrative Review
por: Pergolizzi, Joseph V., et al.
Publicado: (2020)

Suicide by Opioid: Exploring the Intentionality of the Act
por: Pergolizzi, Joseph, et al.
Publicado: (2021)

Safety And Efficacy Of The Unique Opioid Buprenorphine For The Treatment Of Chronic Pain
por: Pergolizzi Jr, Joseph V, et al.
Publicado: (2019)

Constipation in Elderly Patients with Noncancer Pain: Focus on Opioid-Induced Constipation
por: Chokhavatia, Sita, et al.
Publicado: (2016)

Pain Control in Latin America: The Optimized Role of Buprenorphine in the Treatment of Cancer and Noncancer Pain
por: Pergolizzi, Joseph V., et al.
Publicado: (2019)

The unsolved case of “bone-impairing analgesics”: the endocrine effects of opioids on bone metabolism
por: Coluzzi, Flaminia, et al.
Publicado: (2015)

Safety of oral methylnaltrexone for opioid-induced constipation in patients with chronic noncancer pain
por: Rauck, Richard L, et al.
Publicado: (2018)

Satisfaction with Therapy Among Patients with Chronic Noncancer Pain with Opioid-Induced Constipation
por: LoCasale, Robert J., et al.
Publicado: (2016)

A Closer Look at Opioid-Induced Adrenal Insufficiency: A Narrative Review
por: Coluzzi, Flaminia, et al.
Publicado: (2023)

Managing severe pain and abuse potential: the potential impact of a new abuse-deterrent formulation oxycodone/naltrexone extended-release product
por: Pergolizzi, Joseph V, et al.
Publicado: (2018)

Opioid Therapy in Cancer Patients and Survivors at Risk of Addiction, Misuse or Complex Dependency
por: Pergolizzi, Joseph V., et al.
Publicado: (2021)

Update on the role of naldemedine in opioid-induced constipation in patients with chronic noncancer pain
por: BouSaba, Joelle, et al.
Publicado: (2022)

Tapentadol Extended Release in the Treatment of Severe Chronic Low Back Pain and Osteoarthritis Pain
por: Pergolizzi, Joseph V., et al.
Publicado: (2018)

Oral methylnaltrexone does not negatively impact analgesia in patients with opioid-induced constipation and chronic noncancer pain
por: Webster, Lynn R, et al.
Publicado: (2018)

A Randomized Study of Lubiprostone for Opioid-Induced Constipation in Patients with Chronic Noncancer Pain
por: Cryer, Byron, et al.
Publicado: (2014)

Clinical Overview and Considerations for the Management of Opioid-induced Constipation in Patients With Chronic Noncancer Pain
por: Viscusi, Eugene R.
Publicado: (2019)

Analysis of opioid-mediated analgesia in Phase III studies of methylnaltrexone for opioid-induced constipation in patients with chronic noncancer pain
por: Webster, Lynn R, et al.
Publicado: (2015)

Pharmacologic Profile of Naloxegol, a Peripherally Acting µ-Opioid Receptor Antagonist, for the Treatment of Opioid-Induced Constipation
por: Floettmann, Eike, et al.
Publicado: (2017)

Pirates of Clinical Trials
por: Pergolizzi, Joseph, et al.
Publicado: (2023)

Old Drugs and New Challenges: A Narrative Review of Nitazenes
por: Pergolizzi Jr, Joseph, et al.
Publicado: (2023)

Application of human factors engineering (HFE) to the design of a naloxone auto-injector for the treatment of opioid emergencies
por: Raffa, Robert B., et al.
Publicado: (2016)

Analysis of opioid-mediated analgesia in Phase III studies of methylnaltrexone for opioid-induced constipation in patients with chronic noncancer pain [Corrigendum]
Publicado: (2018)

Efficacy and Safety of Prucalopride in Patients with Chronic Noncancer Pain Suffering from Opioid-Induced Constipation
por: Sloots, Cornelius E. J., et al.
Publicado: (2010)

A Randomized, Placebo-Controlled Trial of Lubiprostone for Opioid-Induced Constipation in Chronic Noncancer Pain
por: Jamal, M Mazen, et al.
Publicado: (2015)

Population Exposure‐Response Modeling of Naloxegol in Patients With Noncancer‐Related Pain and Opioid‐Induced Constipation
por: Al‐Huniti, N, et al.
Publicado: (2016)

Pharmacologic effects of naldemedine, a peripherally acting μ‐opioid receptor antagonist, in in vitro and in vivo models of opioid‐induced constipation
por: Kanemasa, Toshiyuki, et al.
Publicado: (2019)

Rehabilitation for Low Back Pain: A Narrative Review for Managing Pain and Improving Function in Acute and Chronic Conditions
por: Pergolizzi, Joseph V., et al.
Publicado: (2020)

Oral methylnaltrexone is efficacious and well tolerated for the treatment of opioid-induced constipation in patients with chronic noncancer pain receiving concomitant methadone
por: Webster, Lynn R, et al.
Publicado: (2018)

European clinical practice recommendations on opioids for chronic noncancer pain – Part 1: Role of opioids in the management of chronic noncancer pain
por: Häuser, Winfried, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6lv1tqb5f22ncprid3i37u2v2o