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Inhibition of Skp2 sensitizes lung cancer cells to paclitaxel

S-phase kinase-associated protein 2 (Skp2) is an E3 ubiquitin ligase and plays an important role in the control of cell cycle progression. Skp2 is upregulated in several cancers, including lung cancers, but the role of Skp2 in the tumorigenesis and anticancer drug resistance in human lung cancer rem...

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Detalles Bibliográficos
Autores principales:	Huang, Tonghai, Yang, Lin, Wang, Guangsuo, Ding, Guanggui, Peng, Bin, Wen, Yuxin, Wang, Zheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261849/ https://www.ncbi.nlm.nih.gov/pubmed/28176922 http://dx.doi.org/10.2147/OTT.S125789

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