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Xiaozhi decoction reduced posthemorrhoidectomy pain and analgesic medication consumption: a prospective study

OBJECTIVE: The aim of this study was to investigate the effect of Xiaozhi decoction (XZD) on posthemorrhoidectomy pain and analgesic medication consumption. METHODS: From May 2013 to March 2015, 315 patients who underwent open hemorrhoidectomy in our hospital were enrolled in this study, of whom, 16...

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Autores principales: Shen, Jianbin, Luo, Xiagang, Zhou, Xiao, Tang, Chengwu, Ju, Huanyu, Xu, Yongqiang, Qin, Lianjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261852/
https://www.ncbi.nlm.nih.gov/pubmed/28176917
http://dx.doi.org/10.2147/JPR.S128500
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author Shen, Jianbin
Luo, Xiagang
Zhou, Xiao
Tang, Chengwu
Ju, Huanyu
Xu, Yongqiang
Qin, Lianjin
author_facet Shen, Jianbin
Luo, Xiagang
Zhou, Xiao
Tang, Chengwu
Ju, Huanyu
Xu, Yongqiang
Qin, Lianjin
author_sort Shen, Jianbin
collection PubMed
description OBJECTIVE: The aim of this study was to investigate the effect of Xiaozhi decoction (XZD) on posthemorrhoidectomy pain and analgesic medication consumption. METHODS: From May 2013 to March 2015, 315 patients who underwent open hemorrhoidectomy in our hospital were enrolled in this study, of whom, 160 patients were randomly assigned to accept sitz bath with warm water after hemorrhoidectomy (control group) and 155 patients were randomly assigned to accept sitz bath with XZD (XZD group) after hemorrhoidectomy. Postoperative pain at 12 hours after surgery and on postoperative days (PODs) 1, 2, 7, 14 and 28 was evaluated by Visual Analog Scale (VAS). Pain on defecation on PODs 1, 2, 7, 14 and 28 was also recorded using the VAS. The consumption of analgesics was also analyzed. RESULTS: No significant difference was found in baseline characteristics between the two groups. Postoperative pain score of the XZD group was significantly lower on POD 2 (6.04±1.11 vs 6.33±1.14, P=0.0229), POD 7 (3.35±0.75 vs 4.22±0.87, P=0.0000) and POD 14 (2.87±0.64 vs 3.64±0.77, P=0.0000) than that of the control group. Similarly, patients in the XZD group experienced significantly less pain on defecation on POD 2 (5.02±1.34 vs 5.43±1.56, P=0.0130), POD 7 (3.08±1.17 vs 3.52±1.29, P=0.0017) and POD 14 (2.31±0.85 vs 2.68±0.99, P=0.0004). Patients in the XZD group consumed significantly less analgesic medication on POD 2 (P=0.0136), POD 7 (P=0.0074) and POD 14 (P=0.0046) than the control group. CONCLUSION: XZD could effectively relieve postoperative pain and reduce analgesic medication consumption after hemorrhoidectomy.
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spelling pubmed-52618522017-02-07 Xiaozhi decoction reduced posthemorrhoidectomy pain and analgesic medication consumption: a prospective study Shen, Jianbin Luo, Xiagang Zhou, Xiao Tang, Chengwu Ju, Huanyu Xu, Yongqiang Qin, Lianjin J Pain Res Original Research OBJECTIVE: The aim of this study was to investigate the effect of Xiaozhi decoction (XZD) on posthemorrhoidectomy pain and analgesic medication consumption. METHODS: From May 2013 to March 2015, 315 patients who underwent open hemorrhoidectomy in our hospital were enrolled in this study, of whom, 160 patients were randomly assigned to accept sitz bath with warm water after hemorrhoidectomy (control group) and 155 patients were randomly assigned to accept sitz bath with XZD (XZD group) after hemorrhoidectomy. Postoperative pain at 12 hours after surgery and on postoperative days (PODs) 1, 2, 7, 14 and 28 was evaluated by Visual Analog Scale (VAS). Pain on defecation on PODs 1, 2, 7, 14 and 28 was also recorded using the VAS. The consumption of analgesics was also analyzed. RESULTS: No significant difference was found in baseline characteristics between the two groups. Postoperative pain score of the XZD group was significantly lower on POD 2 (6.04±1.11 vs 6.33±1.14, P=0.0229), POD 7 (3.35±0.75 vs 4.22±0.87, P=0.0000) and POD 14 (2.87±0.64 vs 3.64±0.77, P=0.0000) than that of the control group. Similarly, patients in the XZD group experienced significantly less pain on defecation on POD 2 (5.02±1.34 vs 5.43±1.56, P=0.0130), POD 7 (3.08±1.17 vs 3.52±1.29, P=0.0017) and POD 14 (2.31±0.85 vs 2.68±0.99, P=0.0004). Patients in the XZD group consumed significantly less analgesic medication on POD 2 (P=0.0136), POD 7 (P=0.0074) and POD 14 (P=0.0046) than the control group. CONCLUSION: XZD could effectively relieve postoperative pain and reduce analgesic medication consumption after hemorrhoidectomy. Dove Medical Press 2017-01-17 /pmc/articles/PMC5261852/ /pubmed/28176917 http://dx.doi.org/10.2147/JPR.S128500 Text en © 2017 Shen et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Shen, Jianbin
Luo, Xiagang
Zhou, Xiao
Tang, Chengwu
Ju, Huanyu
Xu, Yongqiang
Qin, Lianjin
Xiaozhi decoction reduced posthemorrhoidectomy pain and analgesic medication consumption: a prospective study
title Xiaozhi decoction reduced posthemorrhoidectomy pain and analgesic medication consumption: a prospective study
title_full Xiaozhi decoction reduced posthemorrhoidectomy pain and analgesic medication consumption: a prospective study
title_fullStr Xiaozhi decoction reduced posthemorrhoidectomy pain and analgesic medication consumption: a prospective study
title_full_unstemmed Xiaozhi decoction reduced posthemorrhoidectomy pain and analgesic medication consumption: a prospective study
title_short Xiaozhi decoction reduced posthemorrhoidectomy pain and analgesic medication consumption: a prospective study
title_sort xiaozhi decoction reduced posthemorrhoidectomy pain and analgesic medication consumption: a prospective study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261852/
https://www.ncbi.nlm.nih.gov/pubmed/28176917
http://dx.doi.org/10.2147/JPR.S128500
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