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A molecular mechanism of chaperone-client recognition

Molecular chaperones are essential in aiding client proteins to fold into their native structure and in maintaining cellular protein homeostasis. However, mechanistic aspects of chaperone function are still not well understood at the atomic level. We use nuclear magnetic resonance spectroscopy to el...

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Detalles Bibliográficos
Autores principales: He, Lichun, Sharpe, Timothy, Mazur, Adam, Hiller, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5262456/
https://www.ncbi.nlm.nih.gov/pubmed/28138538
http://dx.doi.org/10.1126/sciadv.1601625