Uncovering the forces between nucleosomes using DNA origami

Revealing the energy landscape for nucleosome association may contribute to the understanding of higher-order chromatin structures and their impact on genome regulation. We accomplish this in a direct measurement by integrating two nucleosomes into a DNA origami–based force spectrometer, which enabl...

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Detalles Bibliográficos
Autores principales: Funke, Jonas J., Ketterer, Philip, Lieleg, Corinna, Schunter, Sarah, Korber, Philipp, Dietz, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5262459/
https://www.ncbi.nlm.nih.gov/pubmed/28138524
http://dx.doi.org/10.1126/sciadv.1600974

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