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In vitro pharmacokinetics of anti-psoriatic fumaric acid esters

BACKGROUND: Psoriasis is a chronic inflammatory skin disease that can be successfully treated with a mixture of fumaric acid esters (FAE) formulated as enteric-coated tablets for oral use. These tablets consist of dimethylfumarate (DMF) and salts of monoethylfumarate (MEF) and its main bioactive met...

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Detalles Bibliográficos
Autores principales: Litjens, Nicolle HR, van Strijen, Elisabeth, van Gulpen, Co, Mattie, Herman, van Dissel, Jaap T, Thio, H Bing, Nibbering, Peter H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC526253/
https://www.ncbi.nlm.nih.gov/pubmed/15479475
http://dx.doi.org/10.1186/1471-2210-4-22