Cargando…

In vitro pharmacokinetics of anti-psoriatic fumaric acid esters

BACKGROUND: Psoriasis is a chronic inflammatory skin disease that can be successfully treated with a mixture of fumaric acid esters (FAE) formulated as enteric-coated tablets for oral use. These tablets consist of dimethylfumarate (DMF) and salts of monoethylfumarate (MEF) and its main bioactive met...

Descripción completa

Detalles Bibliográficos
Autores principales:	Litjens, Nicolle HR, van Strijen, Elisabeth, van Gulpen, Co, Mattie, Herman, van Dissel, Jaap T, Thio, H Bing, Nibbering, Peter H
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2004
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC526253/ https://www.ncbi.nlm.nih.gov/pubmed/15479475 http://dx.doi.org/10.1186/1471-2210-4-22

Ejemplares similares

Treatment of lupus erythematosus with fumaric acid ester derivatives: two case-reports
por: Balak, Deepak MW, et al.
Publicado: (2011)

Maggot Secretions Skew Monocyte-Macrophage Differentiation Away from a Pro-Inflammatory to a Pro-Angiogenic Type
por: van der Plas, Mariena J. A., et al.
Publicado: (2009)

Fumaric acid esters in dermatology
por: Wollina, Uwe
Publicado: (2011)

Inflammatory and Antimicrobial Responses to Methicillin-Resistant Staphylococcus aureus in an In Vitro Wound Infection Model
por: Haisma, Elisabeth M., et al.
Publicado: (2013)

Drug-induced Fanconi syndrome associated with fumaric acid esters treatment for psoriasis: a case series
por: Balak, Deepak M.W., et al.
Publicado: (2016)

Fumaric acid esters in the management of psoriasis
por: Balak, Deepak MW
Publicado: (2015)

Treatment of disseminated granuloma annulare with fumaric acid esters
por: Kreuter, Alexander, et al.
Publicado: (2002)

Potential Beneficial Effects of Cytomegalovirus Infection after Transplantation
por: Litjens, Nicolle H. R., et al.
Publicado: (2018)

Switching from a fumaric acid ester mixture to dimethylfumarate monotherapy in psoriasis
por: Warren, R.B., et al.
Publicado: (2019)

Different Fumaric Acid Esters Elicit Distinct Pharmacologic Responses
por: Wipke, Brian T., et al.
Publicado: (2021)

Fumaric Acid and its Esters: An Emerging Treatment for Multiple Sclerosis
por: Moharregh-Khiabani, D, et al.
Publicado: (2009)

Successful treatment of recalcitrant cutaneous sarcoidosis with fumaric acid esters
por: Nowack, Ute, et al.
Publicado: (2002)

Fumaric acid ester‐induced T‐cell lymphopenia in the real‐life treatment of psoriasis
por: Dickel, H., et al.
Publicado: (2019)

Differential effects of age, cytomegalovirus-seropositivity and end-stage renal disease (ESRD) on circulating T lymphocyte subsets
por: Litjens, Nicolle HR, et al.
Publicado: (2011)

Pharmacokinetics and Bioavailability of Monomethyl Fumarate Following a Single Oral Dose of Bafiertam™ (Monomethyl Fumarate) or Tecfidera(®) (Dimethyl Fumarate)
por: Lategan, Thomas W., et al.
Publicado: (2021)

Maggot secretions suppress pro-inflammatory responses of human monocytes through elevation of cyclic AMP
por: van der Plas, M. J. A., et al.
Publicado: (2009)

Dimethyl Fumarate and Its Esters: A Drug with Broad Clinical Utility?
por: Kourakis, Stephanie, et al.
Publicado: (2020)

Efficacy of Fumaric Acid Esters in the R6/2 and YAC128 Models of Huntington's Disease
por: Ellrichmann, Gisa, et al.
Publicado: (2011)

Switch of psoriasis therapy from a fumaric acid ester mixture to dimethyl fumarate monotherapy: Results of a prospective study
por: Falkvoll, Sandra, et al.
Publicado: (2019)

Fumaric acid ester-induced renal Fanconi syndrome: evidence of mitochondrial toxicity
por: Wan, Elizabeth R, et al.
Publicado: (2021)

A Novel Serine Protease Secreted by Medicinal Maggots Enhances Plasminogen Activator-Induced Fibrinolysis
por: van der Plas, Mariena J. A., et al.
Publicado: (2014)

In vitro evaluation of poloxamer in situ forming gels for bedaquiline fumarate salt and pharmacokinetics following intramuscular injection in rats
por: Hemelryck, Sandy Van, et al.
Publicado: (2019)

Comparison of pharmacokinetics and bioavailability of bedaquiline fumarate, benzoate and maleate in dogs
por: Jaw-Tsai, S., et al.
Publicado: (2023)

Population pharmacokinetics of tofacitinib in patients with psoriatic arthritis
por: Xie, Rujia, et al.
Publicado: (2019)

Oral fumaric acid esters for psoriasis: abridged Cochrane systematic review including GRADE assessments
por: Atwan, A., et al.
Publicado: (2016)

Unusual Formation of 1,2,4-Oxadiazine Core in Reaction of Amidoximes with Maleic or Fumaric Esters
por: Presnukhina, Sofia I., et al.
Publicado: (2022)

Physiologically-Based Pharmacokinetic Modelling to Predict the Pharmacokinetics and Pharmacodynamics of Linezolid in Adults and Children with Tuberculous Meningitis
por: Litjens, Carlijn H. C., et al.
Publicado: (2023)

High numbers of differentiated CD28null CD8+ T cells are associated with a lowered risk for late rejection and graft loss after kidney transplantation
por: Betjes, Michiel G. H., et al.
Publicado: (2020)

Role of Nuclear Factor (Erythroid-Derived 2)-Like 2 Signaling for Effects of Fumaric Acid Esters on Dendritic Cells
por: Hammer, Anna, et al.
Publicado: (2017)

Fumaric acid production by fermentation
por: Roa Engel, Carol A., et al.
Publicado: (2008)

Overview of phthalate ester pharmacokinetics in mammalian species.
por: Kluwe, W M
Publicado: (1982)

Expression of Senescence Marker TIGIT Identifies Polyfunctional Donor-Reactive CD4+ T Cells Preferentially Lost After Kidney Transplantation
por: van der List, Amy C. J., et al.
Publicado: (2021)

Development of a Population Pharmacokinetic Model for the Diroximel Fumarate Metabolites Monomethyl Fumarate and 2-Hydroxyethyl Succinimide Following Oral Administration of Diroximel Fumarate in Healthy Participants and Patients with Multiple Sclerosis
por: Kuchimanchi, Mita, et al.
Publicado: (2022)

Fumaric Acid Esters Stimulate Astrocytic VEGF Expression through HIF-1α and Nrf2
por: Wiesner, Diana, et al.
Publicado: (2013)

Mechanisms of Oxidative Damage in Multiple Sclerosis and Neurodegenerative Diseases: Therapeutic Modulation via Fumaric Acid Esters
por: Lee, De-Hyung, et al.
Publicado: (2012)

Physiologically based pharmacokinetic model for the inhibition of acetylcholinesterase by organophosphate esters.
por: Gearhart, J M, et al.
Publicado: (1994)

The FCGR3A 158 V/V-genotype is associated with decreased survival of renal allografts with chronic active antibody-mediated rejection
por: Litjens, Nicolle, et al.
Publicado: (2021)

Protective Cytomegalovirus (CMV)-Specific T-Cell Immunity Is Frequent in Kidney Transplant Patients without Serum Anti-CMV Antibodies
por: Litjens, Nicolle H. R., et al.
Publicado: (2017)

Treatment Duration of Febrile Urinary Tract Infections
por: van der Starre, Willize E., et al.
Publicado: (2011)

Macrophage dysfunction in Psoriatic Arthritis
por: Wenink, Mark H, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_cfuiiop6n701avvbopuj39qlkk