Cargando…
New microRNA Biomarkers for Drug-Induced Steatosis and Their Potential to Predict the Contribution of Drugs to Non-alcoholic Fatty Liver Disease
Background and Aims: Drug-induced steatosis is a major reason for drug failure in clinical trials and post-marketing withdrawal; and therefore, predictive biomarkers are essential. These could be particularly relevant in non-alcoholic fatty liver disease (NAFLD), where most patients show features of...
Autores principales: | López-Riera, Mireia, Conde, Isabel, Tolosa, Laia, Zaragoza, Ángela, Castell, José V., Gómez-Lechón, María J., Jover, Ramiro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263149/ https://www.ncbi.nlm.nih.gov/pubmed/28179883 http://dx.doi.org/10.3389/fphar.2017.00003 |
Ejemplares similares
-
Non-invasive prediction of NAFLD severity: a comprehensive, independent validation of previously postulated serum microRNA biomarkers
por: López-Riera, Mireia, et al.
Publicado: (2018) -
Quantitative Prediction of Steatosis in Patients with Non-Alcoholic Fatty Liver by Means of Hepatic MicroRNAs Present in Serum and Correlating with Hepatic Fat
por: Quintás, Guillermo, et al.
Publicado: (2022) -
Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury
por: Tolosa, Laia, et al.
Publicado: (2017) -
Foxa1 Reduces Lipid Accumulation in Human Hepatocytes and Is Down-Regulated in Nonalcoholic Fatty Liver
por: Moya, Marta, et al.
Publicado: (2012) -
Development of Prediction Models for Drug-Induced Cholestasis, Cirrhosis, Hepatitis, and Steatosis Based on Drug and Drug Metabolite Structures
por: Shin, Hyun Kil, et al.
Publicado: (2020)