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Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging

Gene expression studies suggest that aging of the human brain is determined by a complex interplay of molecular events, although both its region- and cell-type-specific consequences remain poorly understood. Here, we extensively characterized aging-altered gene expression changes across ten human br...

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Detalles Bibliográficos
Autores principales: Soreq, Lilach, Rose, Jamie, Soreq, Eyal, Hardy, John, Trabzuni, Daniah, Cookson, Mark R., Smith, Colin, Ryten, Mina, Patani, Rickie, Ule, Jernej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263238/
https://www.ncbi.nlm.nih.gov/pubmed/28076797
http://dx.doi.org/10.1016/j.celrep.2016.12.011