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Pseudomonas aeruginosa Pore-Forming Exolysin and Type IV Pili Cooperate To Induce Host Cell Lysis
Clinical strains of Pseudomonas aeruginosa lacking the type III secretion system genes employ a toxin, exolysin (ExlA), for host cell membrane disruption. Here, we demonstrated that ExlA export requires a predicted outer membrane protein, ExlB, showing that ExlA and ExlB define a new active two-part...
Autores principales: | Basso, Pauline, Ragno, Michel, Elsen, Sylvie, Reboud, Emeline, Golovkine, Guillaume, Bouillot, Stephanie, Huber, Philippe, Lory, Stephen, Faudry, Eric, Attrée, Ina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263249/ https://www.ncbi.nlm.nih.gov/pubmed/28119472 http://dx.doi.org/10.1128/mBio.02250-16 |
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