Cargando…

Pseudomonas aeruginosa Pore-Forming Exolysin and Type IV Pili Cooperate To Induce Host Cell Lysis

Clinical strains of Pseudomonas aeruginosa lacking the type III secretion system genes employ a toxin, exolysin (ExlA), for host cell membrane disruption. Here, we demonstrated that ExlA export requires a predicted outer membrane protein, ExlB, showing that ExlA and ExlB define a new active two-part...

Descripción completa

Detalles Bibliográficos
Autores principales:	Basso, Pauline, Ragno, Michel, Elsen, Sylvie, Reboud, Emeline, Golovkine, Guillaume, Bouillot, Stephanie, Huber, Philippe, Lory, Stephen, Faudry, Eric, Attrée, Ina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263249/ https://www.ncbi.nlm.nih.gov/pubmed/28119472 http://dx.doi.org/10.1128/mBio.02250-16

Ejemplares similares

Exolysin Shapes the Virulence of Pseudomonas aeruginosa Clonal Outliers
por: Reboud, Emeline, et al.
Publicado: (2017)

Pseudomonas aeruginosa Exolysin promotes bacterial growth in lungs, alveolar damage and bacterial dissemination
por: Bouillot, Stéphanie, et al.
Publicado: (2017)

Pseudomonas aeruginosa Transmigrates at Epithelial Cell-Cell Junctions, Exploiting Sites of Cell Division and Senescent Cell Extrusion
por: Golovkine, Guillaume, et al.
Publicado: (2016)

VE-Cadherin Cleavage by LasB Protease from Pseudomonas aeruginosa Facilitates Type III Secretion System Toxicity in Endothelial Cells
por: Golovkine, Guillaume, et al.
Publicado: (2014)

Pseudomonas aeruginosa ExlA and Serratia marcescens ShlA trigger cadherin cleavage by promoting calcium influx and ADAM10 activation
por: Reboud, Emeline, et al.
Publicado: (2017)

Pseudomonas aeruginosa Takes a Multi-Target Approach to Achieve Junction Breach
por: Golovkine, Guillaume, et al.
Publicado: (2018)

Corrigendum: Pseudomonas aeruginosa Takes a Multi-Target Approach to Achieve Junction Breach
por: Golovkine, Guillaume, et al.
Publicado: (2018)

Functional Consequences of Calcium Influx Promoted by Bacterial Pore-Forming Toxins
por: Bouillot, Stéphanie, et al.
Publicado: (2018)

CLIQ-BID: A method to quantify bacteria-induced damage to eukaryotic cells by automated live-imaging of bright nuclei
por: Wallez, Yann, et al.
Publicado: (2018)

Host cell surfaces induce a Type IV pili-dependent alteration of bacterial swimming
por: Golovkine, Guillaume, et al.
Publicado: (2016)

Structural Basis of Cytotoxicity Mediated by the Type III Secretion Toxin ExoU from Pseudomonas aeruginosa
por: Gendrin, Claire, et al.
Publicado: (2012)

Nanoscale Adhesion Forces of Pseudomonas aeruginosa Type IV Pili
por: Beaussart, Audrey, et al.
Publicado: (2014)

Species-specific recruitment of transcription factors dictates toxin expression
por: Trouillon, Julian, et al.
Publicado: (2020)

Pseudomonas aeruginosa distinguishes surfaces by stiffness using retraction of type IV pili
por: Koch, Matthias D., et al.
Publicado: (2022)

The core and accessory Hfq interactomes across Pseudomonas aeruginosa lineages
por: Trouillon, Julian, et al.
Publicado: (2022)

Transcription Inhibitors with XRE DNA-Binding and Cupin Signal-Sensing Domains Drive Metabolic Diversification in Pseudomonas
por: Trouillon, Julian, et al.
Publicado: (2021)

Insertion sequences drive the emergence of a highly adapted human pathogen
por: Sentausa, Erwin, et al.
Publicado: (2019)

Global Regulatory Pathways Converge To Control Expression of Pseudomonas aeruginosa Type IV Pili
por: Coggan, Kimberly A., et al.
Publicado: (2022)

Structural and Functional Characterization of the Type Three Secretion System (T3SS) Needle of Pseudomonas aeruginosa
por: Lombardi, Charlotte, et al.
Publicado: (2019)

A Filamentous Bacteriophage Protein Inhibits Type IV Pili To Prevent Superinfection of Pseudomonas aeruginosa
por: Schmidt, Amelia K., et al.
Publicado: (2022)

Characterization of Pseudomonas aeruginosa Bacteriophage L5 Which Requires Type IV Pili for Infection
por: Yang, Lan, et al.
Publicado: (2022)

A gacS Deletion in Pseudomonas aeruginosa Cystic Fibrosis Isolate CHA Shapes Its Virulence
por: Sall, Khady Mayebine, et al.
Publicado: (2014)

Intraclonal genome diversity of Pseudomonas aeruginosa clones CHA and TB
por: Bezuidt, Oliver KI, et al.
Publicado: (2013)

Type IV pili—a numbers game
por: Karuppiah, Vijaykumar, et al.
Publicado: (2014)

Complete Genome Sequence of Pseudomonas aeruginosa Podophage MPK7, Which Requires Type IV Pili for Infection
por: Bae, Hee-Won, et al.
Publicado: (2013)

Evidence for the Type IV Pili Retraction Motor PilT as a Component of the Surface Sensing System in Pseudomonas aeruginosa
por: Geiger, C.J., et al.
Publicado: (2023)

ExlA Pore-Forming Toxin: Localization at the Bacterial Membrane, Regulation of Secretion by Cyclic-Di-GMP, and Detection In Vivo
por: Deruelle, Vincent, et al.
Publicado: (2021)

Determination of the two-component systems regulatory network reveals core and accessory regulations across Pseudomonas aeruginosa lineages
por: Trouillon, Julian, et al.
Publicado: (2021)

Role of Type IV Pili in Predation by Bdellovibrio bacteriovorus
por: Chanyi, Ryan M., et al.
Publicado: (2014)

Diversity and Evolution of Type IV pili Systems in Archaea
por: Makarova, Kira S., et al.
Publicado: (2016)

Archaeal type IV pili and their involvement in biofilm formation
por: Pohlschroder, Mechthild, et al.
Publicado: (2015)

Structure and function of minor pilins of type IV pili
por: Jacobsen, Theis, et al.
Publicado: (2019)

Effectiveness of Pseudomonas aeruginosa type VI secretion system relies on toxin potency and type IV pili-dependent interaction
por: Rudzite, Marta, et al.
Publicado: (2023)

Pseudomonas aeruginosa type IV pili actively induce mucus contraction to form biofilms in tissue-engineered human airways
por: Rossy, Tamara, et al.
Publicado: (2023)

Antimicrobial resistance and virulence of Pseudomonas spp. among healthy animals: concern about exolysin ExlA detection
por: Ruiz-Roldán, Lidia, et al.
Publicado: (2020)

Unique Features of a Pseudomonas aeruginosa α2-Macroglobulin Homolog
por: Robert-Genthon, Mylène, et al.
Publicado: (2013)

The type IV pili component PilO is a virulence determinant of Francisella novicida
por: Ozanic, Mateja, et al.
Publicado: (2022)

Pseudomonas aeruginosa type IV minor pilins and PilY1 regulate virulence by modulating FimS-AlgR activity
por: Marko, Victoria A., et al.
Publicado: (2018)

The bacterial toxin ExoU requires a host trafficking chaperone for transportation and to induce necrosis
por: Deruelle, Vincent, et al.
Publicado: (2021)

Involvement of Type IV Pili in Pathogenicity of Plant Pathogenic Bacteria
por: Burdman, Saul, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_lq7euj5s8s5n9o6k3pr2bo5g8i